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Chronic kidney disease (CKD), a chronic progressive condition. In CKD, the kidneys lose their normal capability to function efficiently. Kidneys have a vital role in various body functions, such as waste filtration, maintaining tissue homeostasis, blood pressure, removal of excessive fluids or toxins, and regulating the production of RBCs. With CKD, the ability of the kidneys to filter out the waste product gets compromised. The glomerular filtration rate (GFR) becomes low, which leads to the accumulation of the waste product.
CKD develops gradually and often remains unnoticed initially. The noticeable signs and symptoms appear one after significant kidney damage.