What are semisynthetic penicillins? Give two examples.
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Penicillin can be divided into two groups, namely natural and semisynthetic penicillins. Natural penicillins are produced from the fermentation of the fungus Penicillium chrysogenum. The semisynthetic penicillins, on the other hand, are prepared from (+)-6-aminopenicillanic acid.
Semi-synthetic penicillins include:
Penicillinase-resistant penicillins. Nafcillin, oxacillin and dicloxacillin are penicillinase-resistant penicillins. …
Aminopenicillins. Amoxicillin and ampicillin are aminopenicillins. …
Extended-spectrum penicillins. Piperacillin is an extended-spectrum penicillin.