Why is an Immortalized Cell Line Immortal?
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An immortalized cell line is called “immortal” because it can keep dividing in the lab for a very long time. The cells skip normal cell senescence. In contrast, most primary cells have a built-in limit to how many times they can divide. This happens because of something called telomeres, which are protective caps at the ends of chromosomes. Every time a cell divides, these telomeres get a little shorter, and eventually, the cell stops dividing altogether.