What is the function of sertoli cells ?
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Sertoli cells are a type of cell located in the seminiferous tubules of the testes, responsible for supporting the development and maturation of sperm cells. They are named after the Italian physiologist Enrico Sertoli, who first described them in the late 19th century.
Sertoli cells:
1. Provide nutrients and support to developing sperm cells
2. Regulate the environment within the seminiferous tubules
3. Produce androgen-binding protein (ABP), which concentrates testosterone in the seminiferous tubules
4. Form the blood-testis barrier, a specialized barrier that separates the seminiferous tubules from the bloodstream
5. Play a role in the release of mature sperm