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The mitochondrion is often referred to as the “powerhouse of the cell” because it generates most of the cell’s supply of adenosine triphosphate (ATP), which is used as a source of chemical energy.
Mitochondria are known as the powerhouse of cells. It is because the mitochondrion is the site of cellular respiration where energy in the form of ATP (Adenosine triphosphate) is generated as a result of oxidation of food constituents.